Quantifying AD‐related brain amyloid with linearised progression models: Model‐based vs. data‐based

Abstract Background Brain amyloid‐β (Aβ) is the pathological hallmark of Alzheimer’s disease (AD). In logistic disease models, Aβ accumulation is a sigmoid function of time‐since‐disease‐onset (TSDO) ( figure 1 ). Previous positron emission tomography (PET)‐based models vary accumulation onset(t50) ... View More