WNT-β Catenin Signaling as a Potential Therapeutic Target for Neurodegenerative Diseases: Current Status and Future Perspective

Ramakrishna, Kakarla; Vineela Nalla, Lakshmi; Dumala, Naresh; Venkateswarlu, Kojja; Kasi Viswanadh, Matte; N. Nalluri, Buchi; Chakravarthy, Guntupalli; Duguluri, Sajusha; Singh, Payal; Nand, Sachchida; Kumar, Ashish; Singh, Veer; Kumar Singh, Santosh

doi:10.3390/diseases11030089

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WNT-β Catenin Signaling as a Potential Therapeutic Target for Neurodegenerative Diseases: Current Status and Future Perspective

Published in Diseases • Jun 25, 2023

Authors:

Kakarla Ramakrishna

Lakshmi Vineela Nalla

Naresh Dumala

Abstract

Wnt/β-catenin (WβC) signaling pathway is an important signaling pathway for the maintenance of cellular homeostasis from the embryonic developmental stages to adulthood. The canonical pathway of WβC signaling is essential for neurogenesis, cell proliferation, and neurogenesis, whereas the noncanonic...

Subject

Wnt signaling pathway

Neurogenesis

Amyotrophic lateral sclerosis

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