Meta-analytic evidence of elevated choline, reduced N-acetylaspartate, and normal creatine in schizophrenia and their moderation by measurement quality, echo time, and medication status

S. Yang, Yvonne; Smucny, Jason; Zhang, Huailin; J. Maddock, Richard

doi:10.1016/j.nicl.2023.103461

Public

Meta-analytic evidence of elevated choline, reduced N-acetylaspartate, and normal creatine in schizophrenia and their moderation by measurement quality, echo time, and medication status

Published in NeuroImage Clinical • Jan 1, 2023

Authors:

Yvonne S. Yang

Jason Smucny

Huailin Zhang

Abstract

BACKGROUND: Brain metabolite abnormalities measured with magnetic resonance spectroscopy (MRS) provide insight into pathological processes in schizophrenia. Prior meta-analyses have not yet answered important questions about the influence of clinical and technical factors on neurometabolite abnormal...

Subject

Choline

Creatine

Basal ganglia

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