Roles of Oxidative Stress and Nrf2 Signaling in Pathogenic and Non-Pathogenic Cells: A Possible General Mechanism of Resistance to Therapy

Hammad, Mira; Raftari, Mohammad; Cesário, Rute; Salma, Rima; R. D. V. Godoy, Paulo; Noushin Emami, S.; Haghdoost, Siamak

doi:10.3390/antiox12071371

Public

Roles of Oxidative Stress and Nrf2 Signaling in Pathogenic and Non-Pathogenic Cells: A Possible General Mechanism of Resistance to Therapy

Published in Antioxidants • Jun 30, 2023

Authors:

Mira Hammad

Mohammad Raftari

Rute Cesário

Abstract

The coordinating role of nuclear factor erythroid-2-related factor 2 (Nrf2) in cellular function is undeniable. Evidence indicates that this transcription factor exerts massive regulatory functions in multiple signaling pathways concerning redox homeostasis and xenobiotics, macromolecules, and iron ...

Subject

Transcription factor

Oxidative stress

Cell biology

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