New approach methodologies in human regulatory toxicology – Not if, but how and when!

Schmeisser, Sebastian; Miccoli, Andrea; von Bergen�, Martin; Berggren, Elisabet; Braeuning, Albert; Busch, Wibke; Desaintes, Christian; Gourmelon, Anne; Grafström, Roland; Harrill, Joshua; Härtung, Thomas; Herzler, Matthias; E.N. Kass, George; Kleinstreuer, Nicole; Leist, Marcel; Luijten, Mirjam; Marx‐Stoelting, Philip; Poetz, Oliver; van Ravenzwaay, Bennard; Roggeband, R; Rogiers, Vera; Roth, Adrian; Sandérs, Pascal; S. Thomas, Russell; Marie Vinggaard, Anne; Vinken, Mathieu; van de Water, Bob; Luch, Andreas; Tralau, Tewes

doi:10.1016/j.envint.2023.108082

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New approach methodologies in human regulatory toxicology – Not if, but how and when!

Published in Environment International • Jul 4, 2023

Authors:

Sebastian Schmeisser

Andrea Miccoli

Martin von Bergen�

Abstract

The predominantly animal-centric approach of chemical safety assessment has increasingly come under pressure. Society is questioning overall performance, sustainability, continued relevance for human health risk assessment and ethics of this system, demanding a change of paradigm. At the same time, ...

Subject

Toolbox

Context (archaeology)

Risk assessment

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