Safety and Efficacy of Tenecteplase Compared With Alteplase in Patients With Large Vessel Occlusion Stroke

Bala, Fouzi; Singh, Nishita; Buck, Brian; Ademola, Ayoola; B. Coutts, Shelagh; Deschaintre, Yan; Khosravani, Houman; Appireddy, Ramana; Moreau, F.; Phillips, Stephen; Gubitz, Gord; Tkach, Aleksander; Catanese, Luciana; Dowlatshahi, Dar; Medvedev, George; Mandzia, Jennifer; Pikula, Aleksandra; Shankar, Jai; Williams, Heather; S. Field, Thalia; Manosalva Alzate, Alejandro; Siddiqui, Muzaffar; Zafar, Atif; Imoukhoude, Oje; Hunter, Gary; Alhabli, Ibrahim; Benali, Faysal; Horn, MacKenzie; D. Hill, Michael; Shamy, Michel; T. Sajobi, Tolulope; H. Swartz, Richard; K. Menon, Bijoy; Almekhlafi, Mohammed

doi:10.1001/jamaneurol.2023.2094

Public

Safety and Efficacy of Tenecteplase Compared With Alteplase in Patients With Large Vessel Occlusion Stroke

Published in JAMA Neurology • Jul 10, 2023

Authors:

Fouzi Bala

Nishita Singh

Brian Buck

Abstract

Importance: It is unknown whether intravenous thrombolysis using tenecteplase is noninferior or preferable compared with alteplase for patients with acute ischemic stroke. Objective: To examine the safety and efficacy of tenecteplase compared to alteplase among patients with large vessel occlusion (...

Subject

Tenecteplase

Medicine

Stroke (engine)

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