MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads

Uliano‐Silva, Marcela; Gabriel R. N. Ferreira, João; Krasheninnikova, Ksenia; Blaxter, Mark; Mieszkowska, Nova; Hall, Neil; W. H. Holland, Peter; Durbin, Richard; A. Richards, Thomas; Kersey, Paul; M. Hollingsworth, Peter; Wilson, Willie; D. Twyford, Alex; Gaya, Ester; Lawniczak, Mara; T. Lewis, Owen; R. Broad, Gavin; J. Martin, Fergal; Hart, Michelle; Barnes, Ian; Formenti, Giulio; Abueg, Linelle; Torrance, James; W. Myers, Eugene; Durbin, Richard; Blaxter, Mark; McCarthy, Shane

doi:10.1186/s12859-023-05385-y

Public

MitoHiFi: a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads

Published in BMC Bioinformatics • Jul 18, 2023

Authors:

Marcela Uliano‐Silva

João Gabriel R. N. Ferreira

Ksenia Krasheninnikova

Abstract

BACKGROUND: PacBio high fidelity (HiFi) sequencing reads are both long (15-20 kb) and highly accurate (> Q20). Because of these properties, they have revolutionised genome assembly leading to more accurate and contiguous genomes. In eukaryotes the mitochondrial genome is sequenced alongside the nucl...

Subject

Genome

Biology

Mitochondrial DNA

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