LO-024 Association between severe non-adherence to hydroxychloroquine and SLE flares, damage, and mortality in 660 patients from the SLICC inception cohort

Nguyen, Yann; Blanchet, Benoı̂t; B. Urowitz, Murray; G. Hanly, John; Gordon, Caroline; Bae, Sang‐Cheol; Romero‐Díaz, Juanita; Sánchez‐Guerrero, Jorge; E. Clarke, Ann; Bernatsky, Sasha; J. Wallace, Daniel; Isenberg, David; Rahman, Anisur; T. Merrill, Joan; R. Fortin, Paul; D. Gladman, Dafna; N Bruce, Ian; Petri, Michelle; M. Ginzler, Ellen; Anne Dooley, Mary; Ramsey‐Goldman, Rosalind; Manzi, Susan; Jönsen, Andreas; S. Alarcón, Graciela; FVan Vollenhoven, Ronald; Aranow, Cynthia; Le Guern, Véronique; Mackay, Meggan; Ruiz‐Irastorza, Guillermo; Lin, Sam; İnanç, Murat; Kalunian, Kenneth; Jacobsen, Søren; Peschken, Christine; L. Kamen, Diane; Askanase, Anca; P. Buyon, Jill; Costedoat‐Chalumeau, N.

doi:10.1136/lupus-2023-kcr.25

Public

LO-024 Association between severe non-adherence to hydroxychloroquine and SLE flares, damage, and mortality in 660 patients from the SLICC inception cohort

Published • Jul 1, 2023

Authors:

Yann Nguyen

Benoı̂t Blanchet

Murray B. Urowitz

Abstract

Background Hydroxychloroquine is one of the major treatment of SLE, but its effectiveness is impaired by non-adherence, reported to range from 3% to 85% in SLE patients. Our objective was to assess the associations of severe non-adherence to HCQ, objectively assessed by HCQ serum levels, and risks o...

Subject

Medicine

Hydroxychloroquine

Interquartile range

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