Lactobacillus species ameliorate membranous nephropathy through inhibiting the aryl hydrocarbon receptor pathway via tryptophan‐produced indole metabolites

Miao, Hua; Wang, Yanni; Yu, Xiao‐Yong; Zou, Liang; Guo, Yan; Su, Wei; Liu, Fei; Cao, Gang; Zhao, Ying‐Yong

doi:10.1111/bph.16219

Public

Lactobacillus species ameliorate membranous nephropathy through inhibiting the aryl hydrocarbon receptor pathway via tryptophan‐produced indole metabolites

Published in British Journal of Pharmacology • Aug 19, 2023

Authors:

Hua Miao

Yanni Wang

Xiao‐Yong Yu

Abstract

BACKGROUND AND PURPOSE: Membranous nephropathy (MN) is an immune-mediated glomerular disease in adults. Antibody- and antigen-bonding mechanisms have been largely clarified, but the subepithelium immune complex deposition-mediated downstream molecular mechanisms are currently unresolved. Increasing ...

Subject

Aryl hydrocarbon receptor

Lactobacillus

Lactobacillus casei

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