Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno‐Oncology Biomarker Working Group on Breast Cancer

B Page, David; Broeckx, Glenn; Arif Jahangir, Chowdhury; Verbandt, Sara; R Gupta, Rajarsi; Thagaard, Jeppe; Khiroya, Reena; Kos, Zuzana; Abduljabbar, Khalid; Acosta Haab, Gabriela; Acs, Balazs; Akturk, Guray; S Almeida, Jonas; Alvarado‐Cabrero, Isabel; Azmoudeh‐Ardalan, Farid; Badve, Sunil; Bariyah Baharun, Nurkhairul; R Bellolio, Enrique; Bheemaraju, Vydehi; RM Blenman, Kim; Botinelly Mendonça Fujimoto, Luciana; Bouchmaa, Najat; Burgues, Octavio; Chon U Cheang, Maggie; Ciompi, Francesco; AD Cooper, Lee; Coosemans, An; Corredor, Germán; Luis Dantas Portela, Flavio; Deman, Frederik; Demaria, Sandra; N Dudgeon, Sarah; Elghazawy, Mahmoud; Ely, Scott; Fernandez‐Martín, Claudio; Fineberg, Susan; B Fox, Stephen; M Gallagher, William; M Giltnane, Jennifer; Gnjatic, Sacha; I Gonzalez‐Ericsson, Paula; Grigoriadis, Anita; Halama, Niels; G Hanna, Matthew; Harbhajanka, Aparna; Hardas, Alexandros; N Hart, Steven; Hartman, Johan; Hewitt, Stephen; I Hida, Akira; M Horlings, Hugo; Husain, Zaheed; Hytopoulos, Evangelos; Irshad, Sheeba; AM Janssen, Emiel; Kahila, Mohamed; R Kataoka, Tatsuki; Kawaguchi, Kosuke; Kharidehal, Durga; I Khramtsov, Andrey; Kiraz, Umay; Kirtani, Pawan; L Kodach, Liudmila; Korski, Konstanty; Kovács, Anikó; Laenkholm, Anne‐Vibeke; Lang‐Schwarz, Corinna; Larsimont, Denis; K Lennerz, Jochen; Lerousseau, Marvin; Li, Xiaoxian; Ly, Amy; Madabhushi, Anant; K Maley, Sai; Manur Narasimhamurthy, Vidya; K Marks, Douglas; S McDonald, Elizabeth; Mehrotra, Ravi; Michiels, Stefan; ul Amir Afsar Minhas, Fayyaz; Mittal, Shachi; A Moore, David; Mushtaq, Shamim; Nighat, Hussain; Papathomas, Thomas; Penault‐Llorca, Frederique; D Perera, Rashindrie; J Pinard, Christopher; Carlos Pinto‐Cardenas, Juan; Pruneri, Giancarlo; Pusztai, Lajos; Rahman, Arman; Mahmood Rajpoot, Nasir; Leon Rapoport, Bernardo; T Rau, Tilman; S Reis‐Filho, Jorge; M Ribeiro, Joana; Rimm, David; Vincent‐Salomon, Anne; Salto‐Tellez, Manuel; Saltz, Joel; Sayed, Shahin; P Siziopikou, Kalliopi; Sotiriou, Christos; Stenzinger, Albrecht; A Sughayer, Maher; Sur, Daniel; Symmans, Fraser; Tanaka, Sunao; Taxter, Timothy; Tejpar, Sabine; Teuwen, Jonas; Aubrey Thompson, E; Tramm, Trine; T Tran, William; van der Laak, Jeroen; J van Diest, Paul; E Verghese, Gregory; Viale, Giuseppe; Vieth, Michael; Wahab, Noorul; Walter, Thomas; Waumans, Yannick; Y Wen, Hannah; Yang, Wentao; Yuan, Yinyin; Adams, Sylvia; Mark Seaverns Bartlett, John; Loibl, Sibylle; Denkert, Carsten; Savas, Peter; Loi, Sherene; Salgado, Roberto; Specht Stovgaard, Elisabeth

doi:10.1002/path.6165

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Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno‐Oncology Biomarker Working Group on Breast Cancer

Shared by NobleBlocks on Aug 1, 2023 • 12:00 AM UTC

Authors:

David B Page

Glenn Broeckx

Chowdhury Arif Jahangir

Abstract

Abstract Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in the tumor microenvironment. However, there exists no standardized method for describing or analyzing spatial immune cell data, and mos...

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