Early detection of liver injuries by the Serum enhanced binding test sensitive to albumin post-transcriptional modifications

SE, Balkhi; MA, Rahali; R, Lakis; FL, Sauvage; M, Martin; A, Janaszkiewicz; R, Lawson; R, Goncalves; P, Carrier; V, Loustaud-Ratti; A, Guyot; P, Marquet; FD, Meo; F, Saint-Marcoux

doi:10.21203/rs.3.rs-3228457/v1

Public

Early detection of liver injuries by the Serum enhanced binding test sensitive to albumin post-transcriptional modifications

Shared by NobleBlocks on Aug 29, 2023 • 12:00 AM UTC

Authors:

Balkhi SE

Rahali MA

Lakis R

Abstract

Background: Early and sensitive biomarkers of liver dysfunction and drug-induced liver injury (DILI) are still needed, both for patient care and drug development. Methods: : We developed the Serum Enhanced Binding (SEB) test to reveal post-transcriptional modifications (PTMs) of human serum albumin ...

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