Exploring the crosstalk between endothelial cells, immune cells, and immune checkpoints in the tumor microenvironment: new insights and therapeutic implications

Fang, Jianwen; Lu, Yue; Zheng, Jingyan; Jiang, Xiaocong; Shen, Haixing; Xi, Shang; Lu, Yuexin; Fu, Peifen

doi:10.1038/s41419-023-06119-x

Public

Exploring the crosstalk between endothelial cells, immune cells, and immune checkpoints in the tumor microenvironment: new insights and therapeutic implications

Published in Cell Death and Disease • Sep 4, 2023

Authors:

Jianwen Fang

Yue Lu

Jingyan Zheng

Abstract

The tumor microenvironment (TME) is a highly intricate milieu, comprising a multitude of components, including immune cells and stromal cells, that exert a profound influence on tumor initiation and progression. Within the TME, angiogenesis is predominantly orchestrated by endothelial cells (ECs), w...

Subject

Crosstalk

Immune system

Tumor microenvironment

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