A foundation model for generalizable disease detection from retinal images

Zhou, Yukun; A. Chia, Mark; K. Wagner, Siegfried; Seçkin Ayhan, Murat; J. Williamson, Dominic; Struyven, Robbert; Liu, Timing; Xu, Moucheng; G. Lozano, Mateo; Woodward-Court, Peter; Kihara, Yuka; E. Allen, Naomi; Gallacher, John; J. Littlejohns, Thomas; Aslam, Tariq; Bishop, Paul; C. Black, Graeme; I. Sergouniotis, Panagiotis; Atan, Denize; D. Dick, Andrew; Williams, Cathy; Barman, Sarah; H. Barrett, Jenny; Mackie, Sarah; Braithwaite, Tasanee; O. Carare, Roxana; Ennis, Sarah; Whitney Gibson, Jane; Lotery, Andrew; Self, Jay; Chakravarthy, Usha; Hogg, Ruth; Paterson, Euan; V. Woodside, Jayne; Pető, Tünde; J. McKay, Gareth; McGuinness, Bernadette; J. Foster, Paul; Balaskas, Konstantinos; P. Khawaja, Anthony; Pontikos, Nikolas; S. Rahi, Jugnoo; Lascaratos, Gerassimos; J. Patel, Praveen; Chan, Michelle; Chua, Sharon; Day, Alexander; Desai, Parul; Egan, Cathy; Fruttiger, Marcus; F. Garway‐Heath, David; J. Hardcastle, Alison; T. Khaw, Peng; Moore, Tony; Sivaprasad, Sobha; G. Strouthidis, Nicholas; Thomas, Dhanes; Tufail, Adnan; C. Viswanathan, Ananth; Dhillon, Bal; MacGillivray, Tom; Sudlow, Cathie; Vitart, Véronique; S. F. Doney, Alex; Trucco, Emanuele; A. Guggeinheim, Jeremy; E. Morgan, James; J. Hammond, Christopher; Williams, Katie; G. Hysi, Pirro; Harding, Simon; Zheng, Yalin; Luben, Robert; J. Luthert, Philip; Sun, Zihan; McKibbin, Martin; O’Sullivan, Eoin; A. Oram, Richard; Weedon, Mike; G. Owen, Christopher; R. Rudnicka, Alicja; Sattar, Naveed; Steel, David; Stratton, Irene; J. Tapp, Robyn; Yates, Max; Petzold, Axel; Madhusudhan, Savita; Altmann, André; Lee, Aaron; J. Topol, Eric; K. Denniston, Alastair; C. Alexander, Daniel; A. Keane, Pearse

doi:10.1038/s41586-023-06555-x

Public

A foundation model for generalizable disease detection from retinal images

Published in Nature • Sep 13, 2023

Authors:

Yukun Zhou

Mark A. Chia

Siegfried K. Wagner

Abstract

Abstract Medical artificial intelligence (AI) offers great potential for recognizing signs of health conditions in retinal images and expediting the diagnosis of eye diseases and systemic disorders 1 . However, the development of AI models requires substantial annotation and models are usually task-...

Subject

Computer science

Artificial intelligence

Generalizability theory

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