Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions

S. McIntyre, Roger; Alsuwaidan, Mohammad; T. Baune, Bernhard; Berk, Michael; Demyttenaere, Koen; F. Goldberg, Joseph; Gorwood, Philip; Ho, Roger; Kasper, Siegfried; H. Kennedy, Sidney; T Ly-Uson, Josefina; B. Mansur, Rodrigo; Hamish McAllister‐Williams, R.; W. Murrough, James; B. Nemeroff, Charles; A. Nierenberg, Andrew; D. Rosenblat, Joshua; Sanacora, Gerard; F. Schatzberg, Alan; C. Shelton, Richard; M. Stahl, Stephen; H. Trivedi, Madhukar; Vieta, Eduard; Vinberg, Maj; Williams, Nolan; H. Young, Allan; Maj, Mario

doi:10.1002/wps.21120

Public

Treatment‐resistant depression: definition, prevalence, detection, management, and investigational interventions

Published in World Psychiatry • Sep 15, 2023

Authors:

Roger S. McIntyre

Mohammad Alsuwaidan

Bernhard T. Baune

Abstract

Treatment-resistant depression (TRD) is common and associated with multiple serious public health implications. A consensus definition of TRD with demonstrated predictive utility in terms of clinical decision-making and health outcomes does not currently exist. Instead, a plethora of definitions hav...

Subject

Medicine

Quetiapine

Aripiprazole

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