Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes

J. Appel, Lawrence; E. Grams, Morgan; Woodward, Mark; Harris, Katie; Arima, Hisatomi; Chalmers, John; Yatsuya, Hiroshi; Tamakoshi, Koji; Li, Yuanying; Coresh, Josef; Sang, Yingying; Matsushita, Kunihiro; Polkinghorne, Kevan; J. Chadban, Steven; Levin, Adeera; Djurdjev, Ognjenka; Tang, Mila; Zhang, Luxia; Wang, Fang; Wang, Jinwei; Zhao, Ming‐Hui; Schäeffner, Elke; Ebert, Natalie; Mielke, Nina; Tonelli, Marcello; Lloyd, Anita; M. Sacks, Frank; G. Shlipak, Michael; Bansal, Nisha; J. Sarnak, Mark; Yamagishi, Kazumasa; Muraki, Isao; Shimizu, Yūji; Iso, Hiroyasu; Fukagawa, Masafumi; Maruyama, Shoichi; Hamano, Takayuki; Fujii, Naohiko; Imaizumi, Takahiro; Alencar de Pinho, Natália; Metzger, Marie; Stengel, Bénédicte; Hamroun, Aghilès; Massy, Ziad; H. Jafar, Tazeen; Jehan, Imtiaz; Hatcher, Juanita; Chaturvedi, Nish; R Poulter, Neil; C. Wheeler, David; Landray, Martin; Anderson, Amanda; Chen, Jing; Lash, James; Taliercio, Jon; Yang, Peter; R. Tuttle, Katherine; Alicic, Radica; B. Nicholas, Susanne; I. Shen, Jenny; Schöttker, Ben; Stocker, Hannah; Rothenbacher, Dietrich; Brenner, Hermann; Levy, Daniel; Hwang, Shih‐Jen; P. Schneider, Markus; Köttgen, Anna; Meiselbach, Heike; Eckardt, Kai‐Uwe; R. Chang, Alex; A. Green, Jamie; Lester Kirchner, H.; Singh, Gurmukteshwar; Sawhney, Simon; Black, Corri; Wilde, Katie; Marks, Angharad; Bell, Samira; K. Siddiqui, Moneeza; Palmer, Colin; R. Pearson, Ewan; Miyazaki, Mariko; Nakayama, Masaaki; Yamamoto, Tae; Yamada, Gen; Ito, Sadayoshi; Círillo, Massimo; Yee‐Moon Wang, Angela; H. L. Wu, Henry; Ching Cheung, Hoi; Ngai, Victoria; Ka Tak, Tang; X. Garg, Amit; McArthur, Eric; Young, Ann; Jha, Vivekanand; Kumar Yadav, Ashok; Kumar, Vivek; P. Carson, April; A Young, Bessie; J. Diamantidis, Clarissa; Min, Yuan‐I; S. Purnell, Tanjala; Ishikawa, Shizukiyo; Mieno, Makiko; Yamagata, Kunihiro; Iseki, Kunitoshi; Asahi, Koichi; Konta, Tsuneo; J. Lee, Brian; J. Brunskill, Nigel; J. Gray, Laura; Major, Rupert; Medcalf, James; Chodick, Gabriel; Melzer Cohen, Cheli; F.M. Wetzels, Jack; J. Blankestijn, Peter; D. van Zuilen, Arjan; A. Inker, Lesley; S. Levey, Andrew; H. Ix, Joachim; H. de Boer, Ian; Katz, Ronit; Kronenberg, Florian; Kollerits, Barbara; Ritz, Eberhard; Nitsch, Dorothea; N. Nadkarni, Girish; Chan, Lili; P. Böttinger, Erwin; Oh, Won-Suk; Liu, Zhihong; Zhang, Haitao; Zhang, Lihua; Manuel Valdivielso, José; Bermúdez-López, Marcelino; Božić, Milica; Caus, Maite; Miguel Díaz‐Tocados, Juan; Stengel, Bénédicte; Miura, Katsuyuki; Ueshima, Hirotsugu; Okayama, Akira; Kadota, Aya; Okamura, Tomonori; Solá, Laura; Ferreiro, Alejandro; Luis Santiago, José; Ríos, Pablo; Gadola, Liliana; Silvariño, Ricardo; Ohkubo, Takayoshi; Satoh, Michihiro; Metoki, Hirohito; Kikuya, Masahiro; L. Ciemins, Elizabeth; T. Mohl, Jeff; G. Nelson, Robert; L. Hanson, Robert; C. Looker, Helen; T. Gansevoort, Ron; M. Kieneker, Lyanne; J. L. Bakker, Stephan; Moranne, Olivier; Couchoud, Cécile; Shepherd, David; K Jassal, Simerjot; Bergstrom, Jaclyn; P. Kövesdy, Csaba; Sumida, Keiichi; Shrestha, Prabin; M. Gutiérrez, Orlando; L. Cheung, Katharine; Muntner, Paul; O. Ilori, Titilayo; J. Pena, Michelle; J.L. Heerspink, Hiddo; L. Fu, Edouard; Elinder, Carl‐Gustaf; Bárány, Peter; Jesús Carrero, Juan; Evans, Marie; Sabanayagam, Charumathi; Cheng, Ching‐Yu; Yin Wong, Tien; Yuen, C; G. Herrington, William; Staplin, Natalie; J Landray, Martin; Baigent, Colin; A. Kalra, Philip; Chinnadurai, Rajkumar; Green, Darren; Sinha, Smeeta; Ritchie, James; L.J. Visseren, Frank; Burger, Pascal; H Emmelot, M; J. van Welzen, Berend; John, Oommen; Gummidi, Balaji; Ghosh, Arpita; Naimark, David; Tangri, Navdeep; Wen, Chi-Pang; Tsai, Min‐Kuang; Ueno, Yoshiyuki; Watanabe, Masafumi; Ichikawa, Kazunobu; Mirbolouk, Mohammadhassan; Azizi, Fereidoun; Hadaegh, Farzad; Hosseinpanah, Farhad; Shi, Wen; E. Arking, Dan; Ärnlöv, Johan; Larsson, Anders; Giedraitis, Vilmantas; B. Mark, Patrick; P. Traynor, Jamie; L. Sullivan, Michael; S. Lees, Jennifer; Won Yang, Jae; il Shin, Jae; Young Lee, Jun; seok Kim, Jae; J.G. Bilo, Henk; R. van Dijk, Peter; A. Edens, Mireille; Dille, Joep; H. Ballew, Shoshana; Jesús Carrero, Juan; E. Grams, Morgan; Chen, Jingsha; Surapaneni, Aditya; E. Grams, Morgan; Coresh, Josef; Matsushita, Kunihiro; H. Ballew, Shoshana; Sang, Yingying; Surapaneni, Aditya; Alencar de Pinho, Natália; Anderson, Amanda; J. Appel, Lawrence; Ärnlöv, Johan; Azizi, Fereidoun; Bansal, Nisha; Bell, Samira; J.G. Bilo, Henk; J. Brunskill, Nigel; Jesús Carrero, Juan; J. Chadban, Steven; Chalmers, John; Chen, Jing; L. Ciemins, Elizabeth; Círillo, Massimo; Ebert, Natalie; Evans, Marie; Ferreiro, Alejandro; L. Fu, Edouard; Fukagawa, Masafumi; A. Green, Jamie; M. Gutiérrez, Orlando; G. Herrington, William; Hwang, Shih‐Jen; A. Inker, Lesley; Iseki, Kunitoshi; H. Jafar, Tazeen; K Jassal, Simerjot; Jha, Vivekanand; Kadota, Aya; Katz, Ronit; Köttgen, Anna; Konta, Tsuneo; Kronenberg, Florian; J. Lee, Brian; S. Lees, Jennifer; Levin, Adeera; C. Looker, Helen; Major, Rupert; Melzer Cohen, Cheli; Mieno, Makiko; Miyazaki, Mariko; Moranne, Olivier; Muraki, Isao; Naimark, David; Nitsch, Dorothea; Oh, Won-Suk; J. Pena, Michelle; S. Purnell, Tanjala; Sabanayagam, Charumathi; Satoh, Michihiro; Sawhney, Simon; Schäeffner, Elke; Schöttker, Ben; I. Shen, Jenny; G. Shlipak, Michael; Sinha, Smeeta; Stengel, Bénédicte; Sumida, Keiichi; Tonelli, Marcello; Manuel Valdivielso, José; D. van Zuilen, Arjan; L.J. Visseren, Frank; Yee‐Moon Wang, Angela; Wen, Chi-Pang; C. Wheeler, David; Yatsuya, Hiroshi; Yamagata, Kunihiro; Won Yang, Jae; Young, Ann; Zhang, Haitao; Zhang, Luxia; S. Levey, Andrew; T. Gansevoort, Ron

doi:10.1001/jama.2023.17002

Public

Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes

Published in JAMA • Oct 3, 2023

Authors:

Lawrence J. Appel

Morgan E. Grams

Mark Woodward

Abstract

Importance: Chronic kidney disease (low estimated glomerular filtration rate [eGFR] or albuminuria) affects approximately 14% of adults in the US. Objective: To evaluate associations of lower eGFR based on creatinine alone, lower eGFR based on creatinine combined with cystatin C, and more severe alb...

Subject

Medicine

Albuminuria

Renal function

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