Modulation of EGFR Activity by Molecularly Imprinted Polymer Nanoparticles Targeting Intracellular Epitopes

Piletsky, Stanislav; Piletsky, Stanislav; V. Baidyuk, E.; Piletska, Elena; Lezina, Larissa; G. Shevchenko, Konstantin; J. L. Jones, Donald; Huy Cao, Thong; Singh, Raj; C. Spivey, Alan; O. Aboagye, Eric; A. Piletsky, Sergey; A. Piletsky, Sergey; A. Barlev, Nickolai

doi:10.1021/acs.nanolett.3c01374

Public

Modulation of EGFR Activity by Molecularly Imprinted Polymer Nanoparticles Targeting Intracellular Epitopes

Published in Nano Letters • Oct 30, 2023

Authors:

Stanislav Piletsky

E. V. Baidyuk

Abstract

In recent years, molecularly imprinted polymer nanoparticles (nanoMIPs) have proven to be an attractive alternative to antibodies in diagnostic and therapeutic applications. However, several key questions remain: how suitable are intracellular epitopes as targets for nanoMIP binding? And to what ext...

Subject

Epitope

Intracellular

Autophosphorylation

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