APOBEC3 deaminase editing in mpox virus as evidence for sustained human transmission since at least 2016

O’Toole, Áine; A. Neher, Richard; Ndodo, Nnaemeka; Borges, Vítor; Gannon, Ben; Paulo Gomes, João; Groves, Natalie; J. King, David; Maloney, Daniel; Lemey, Philippe; Lewandowski, Kuiama; J. Loman, Nicholas; Myers, Richard; F. Omah, Ifeanyi; A. Suchard, Marc; Worobey, Michael; Chand, Meera; Ihekweazu, Chikwe; Ulaeto, David; Adetifa, Ifedayo; Rambaut, Andrew

doi:10.1126/science.adg8116

Public

APOBEC3 deaminase editing in mpox virus as evidence for sustained human transmission since at least 2016

Published in Science • Nov 2, 2023

Authors:

Áine O’Toole

Richard A. Neher

Nnaemeka Ndodo

Abstract

Historically, mpox has been characterized as an endemic zoonotic disease that transmits through contact with the reservoir rodent host in West and Central Africa. However, in May 2022, human cases of mpox were detected spreading internationally beyond countries with known endemic reservoirs. When th...

Subject

Transmission (telecommunications)

Biology

Zoonosis

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