Validation of MSIntuit as an AI-based pre-screening tool for MSI detection from colorectal cancer histology slides

Saillard, Charlie; Dubois, Rémy; Tchita, Oussama; Loiseau, Nicolas; Garcia, Thierry; Adriansen, Aurélie; Carpentier, Séverine; Reyre, J.; Enéa, Diana; von Loga, Katharina; Kamoun, Aurélie; Rossat, Stéphane; Wiscart, Corentin; Sefta, Meriem; Auffret, Michaël; Guillou, Lionel; Fouillet, Arnaud; Nikolas Kather, Jakob; Svrcek, Magali

doi:10.1038/s41467-023-42453-6

Public

Validation of MSIntuit as an AI-based pre-screening tool for MSI detection from colorectal cancer histology slides

Published in Nature Communications • Nov 6, 2023

Authors:

Charlie Saillard

Rémy Dubois

Oussama Tchita

Abstract

Mismatch Repair Deficiency (dMMR)/Microsatellite Instability (MSI) is a key biomarker in colorectal cancer (CRC). Universal screening of CRC patients for MSI status is now recommended, but contributes to increased workload for pathologists and delayed therapeutic decisions. Deep learning has the pot...

Subject

Microsatellite instability

Colorectal cancer

Medicine

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