AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences

Váradi, Mihály; Bertoni, Damian; Magaña, Paulyna; Paramval, Urmila; Pidruchna, Ivanna; Radhakrishnan, Malarvizhi; Tsenkov, Maxim; Nair, Sreenath; Mirdita, Milot; Yeo, Jingi; Kovalevskiy, Oleg; Tunyasuvunakool, Kathryn; Laydon, Agata; Žídek, Augustin; Tomlinson, Hamish; Hariharan, Dhavanthi; Abrahamson, Josh; Green, Tim; Jumper, John; Birney, Ewan; Steinegger, Martin; Hassabis, Demis; Velankar, Sameer

doi:10.1093/nar/gkad1011

Public

AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences

Published in Nucleic Acids Research • Oct 18, 2023

Authors:

Mihály Váradi

Damian Bertoni

Paulyna Magaña

Abstract

The AlphaFold Database Protein Structure Database (AlphaFold DB, https://alphafold.ebi.ac.uk) has significantly impacted structural biology by amassing over 214 million predicted protein structures, expanding from the initial 300k structures released in 2021. Enabled by the groundbreaking AlphaFold2...

Subject

Biology

Protein structure

Computational biology

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