Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T-cell Therapy: A Retrospective Study Analyzing Risks, Outcomes, and Healthcare Burden

Patel, Rushin; Patel, Mrunal; Laxmidhar, Fehmida; Lakhatariya, Khushboo; Patel, Darshil; Patel, Zalak; Shaikh, Safia

doi:10.7759/cureus.49452

Public

Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T-cell Therapy: A Retrospective Study Analyzing Risks, Outcomes, and Healthcare Burden

Published in Cureus • Nov 26, 2023

Authors:

Rushin Patel

Mrunal Patel

Fehmida Laxmidhar

Abstract

Background Chimeric antigen receptor T-cell (CAR-T) therapy has emerged as a promising immunotherapy for various malignancies. However, its use is associated with challenges, including cytokine release syndrome (CRS), a potentially severe complication. This retrospective study aims to analyze the ri...

Subject

Medicine

Confidence interval

Odds ratio

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