Single‐cell and spatial transcriptomics reveal
                    <i>POSTN</i>
                    <sup>+</sup>
                    cancer‐associated fibroblasts correlated with immune suppression and tumour progression in non‐small cell lung cancer

Chen, Chao; Guo, Qiang; Liu, Yang; Hou, Qinghua; Liao, Mengying; Guo, Yanying; Zang, Yupeng; Wang, Fei; Liu, Huanyu; Luan, Xinyu; Liang, Yanling; Guan, Zhuojue; Li, Yanling; Liu, Haozhen; Dong, Xuan; Zhang, Xiuqing; Liu, Jixian; Xu, Qumiao

doi:10.1002/ctm2.1515

Public

Single‐cell and spatial transcriptomics reveal POSTN + cancer‐associated fibroblasts correlated with immune suppression and tumour progression in non‐small cell lung cancer

Shared by NobleBlocks on Dec 1, 2023 • 12:00 AM UTC

Authors:

Chao Chen

Qiang Guo

Yang Liu

Abstract

Abstract Background Cancer‐associated fibroblasts (CAFs) are potential targets for cancer therapy. Due to the heterogeneity of CAFs, the influence of CAF subpopulations on the progression of lung cancer is still unclear, which impedes the translational advances in targeting CAFs. Methods We performe...

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