Differential associations between regional amyloid PET and Alzheimer’s disease polygenic risk scores

S. Luckett, Emma; E. Collij, Lyduine; Lorenzini, Luigi; Tesi, Niccoló; Vilor‐Tejedor, Natàlia; Vállez García, David; Lopes Alves, Isadora; Shekari, Mahnaz; Meije Wink, Alle; Payoux, Pierre; Dubois, Bruno; Grau‐Rivera, Oriol; Boada, Merçé; Nordberg, Agneta; Scheltens, Philip; Schöll, Michael; Wolz, Robin; E. Schmidt, Mark; Gismondi, Rossella; Stephens, Andrew; Buckley, Christopher; B. Frisoni, Giovanni; Hanseeuw, Bernard; Jelle Visser, Pieter; Vandenberghe, Rik; Farrar, Gill; Domingo Gispert, Juan; Ritchie, Craig; Barkhof, Frederik

doi:10.1002/alz.071266

Public

Differential associations between regional amyloid PET and Alzheimer’s disease polygenic risk scores

Published in Alzheimer s & Dementia • Dec 1, 2023

Authors:

Emma S. Luckett

Lyduine E. Collij

Luigi Lorenzini

Abstract

Abstract Background We previously described three spatio‐temporal subtypes of amyloid accumulation trajectories, measured with PET (Collij et al., 2022). APOE4 carriers tended to have initial amyloid deposition in frontal regions compared to those showing initial deposition in parietal and occipital...

Subject

Precuneus

Amyloid (mycology)

Disease

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