Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy

Chehelgerdi, Mohammad; Chehelgerdi, Matin; Khorramian‐Ghahfarokhi, Milad; Shafieizadeh, Marjan; Mahmoudi, Esmaeil; Eskandari, Fatemeh; Rashidi, Mohsen; Arshi, Asghar; Mokhtari-Farsani, Abbas

doi:10.1186/s12943-023-01925-5

Public

Comprehensive review of CRISPR-based gene editing: mechanisms, challenges, and applications in cancer therapy

Published in Molecular Cancer • Jan 9, 2024

Authors:

Mohammad Chehelgerdi

Matin Chehelgerdi

Milad Khorramian‐Ghahfarokhi

Abstract

The CRISPR system is a revolutionary genome editing tool that has the potential to revolutionize the field of cancer research and therapy. The ability to precisely target and edit specific genetic mutations that drive the growth and spread of tumors has opened up new possibilities for the developmen...

Subject

CRISPR

Genome editing

Cancer therapy

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