Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology

J. Ashton, Nicholas; S. Brum, Wagner; Di Molfetta, Guglielmo; L. Benedet, Andrea; Arslan, Burak; Jonaitis, Erin; E. Langhough, Rebecca; Cody, Karly; Wilson, Rachael; M. Carlsson, Cynthia; Vanmechelen, Eugeen; Montoliu-Gaya, Laia; Lantero-Rodriguez, Juan; Rahmouni, Nesrine; Tissot, Cecile; Stevenson, Jenna; Servaes, Stijn; Therriault, Joseph; Pascoal, Tharick; Lleó, Alberto; Alcolea, Daniel; Fortea, Juan; Rosa-Neto, Pedro; Johnson, Sterling; Jeromin, Andreas; Blennow, Kaj; Zetterberg, Henrik

doi:10.1001/jamaneurol.2023.5319

Public

Diagnostic Accuracy of a Plasma Phosphorylated Tau 217 Immunoassay for Alzheimer Disease Pathology

Shared by NobleBlocks on Mar 1, 2024 • 12:00 AM UTC

Authors:

Nicholas J. Ashton

Wagner S. Brum

Guglielmo Di Molfetta

Abstract

Importance Phosphorylated tau (p-tau) is a specific blood biomarker for Alzheimer disease (AD) pathology, with p-tau217 considered to have the most utility. However, availability of p-tau217 tests for research and clinical use has been limited. Expanding access to this highly accurate AD biomarker i...

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