Intravenous tenecteplase compared with alteplase for minor ischaemic stroke: a secondary analysis of the AcT randomised clinical trial

Nair, Radhika; Singh, Nishita; Kate, Mahesh; Asdaghi, Negar; Joseph Sarmiento, Robert; Bala, Fouzi; B. Coutts, Shelagh; Horn, MacKenzie; Y. Poppe, Alexandre; Williams, Heather; Ademola, Ayoola; Alhabli, Ibrahim; Benali, Faysal; Khosravani, Houman; R. Hunter, Gary; Tkach, Aleksander; Alejandro Manosalva Alzate, Herbert; Pikula, Aleksandra; S. Field, Thalia; Trivedi, Anurag; Dowlatshahi, Dar; Catanese, Luciana; Shuaib, Ashfaq; M. Demchuk, Andrew; T. Sajobi, Tolulope; Almekhlafi, Mohammed; H. Swartz, Richard; K. Menon, Bijoy; Buck, Brian

doi:10.1136/svn-2023-002828

Public

Intravenous tenecteplase compared with alteplase for minor ischaemic stroke: a secondary analysis of the AcT randomised clinical trial

Published in Stroke and Vascular Neurology • Jan 31, 2024

Authors:

Radhika Nair

Nishita Singh

Mahesh Kate

Abstract

BACKGROUND: In ischaemic stroke, minor deficits (National Institutes of Health Stroke Scale (NIHSS) ≤5) at presentation are common but often progress, leaving patients with significant disability. We compared the efficacy and safety of intravenous thrombolysis with tenecteplase versus alteplase in p...

Subject

Tenecteplase

Medicine

Thrombolysis

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