Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity

M. Koskinen, Leena; Nieminen, Lari; Arjonen, Antti; Guzmán, Camilo; Peurla, Markus; Peuhu, Emilia

doi:10.1007/s10911-024-09557-1

Public

Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity

Published in Journal of Mammary Gland Biology and Neoplasia • Feb 28, 2024

Authors:

Leena M. Koskinen

Lari Nieminen

Antti Arjonen

Abstract

The three-dimensional (3D) structure of the ductal epithelium and the surrounding extracellular matrix (ECM) are integral aspects of the breast tissue, and they have important roles during mammary gland development, function and malignancy. However, the architecture of the branched mammary epithelia...

Subject

Biology

Morphogenesis

3D bioprinting

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