Decreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component POT1

Spano, Luana; Marie‐Claire, Cynthia; Godin, Ophélia; Lebras, Apolline; Courtin, Cindie; Laplanche, Jean; Leboyer, Marion; Aouizerate, Bruno; Lefrère, Antoine; Belzeaux, Raoul; Courtet, Philippe; Olié, Émilie; Dubertret, Caroline; Schwan, Raymund; Aubin, V.; Roux, Paul; Polosan, Mircea; Samalin, Ludovic; Haffen, Émmanuel; Étain, Bruno; Olié, E.; Leboyer, Marion; Haffen, Émmanuel; Llorca, Pierre‐Michel; Barteau, V.; Bensalem, S.; Godin, Ophélia; Laouamri, H.; Souryis, K.; Hotier, S.; Pelletier, Agnès; Drancourt, Noëmie; P. Sánchez, Juliana; Saliou, E.; Hebbache, C.; Petrucci, J.; Willaume, L.; Bourdin, E.; Bellivier, Frank; Étain, Bruno; Hennion, Vincent; Marlinge, Emeline; Lebard, Pierre; Antoniol, B.; Desage, A.; Gard, Sébastien; Jutant, A.; M’Baïlara, Katia; Minois, I.; Zanouy, L.; Abettan, C.; Bardin, Laurent; Cazals, A.; Courtet, Philippe; Deffinis, B.; Ducasse, Déborah; Gachet, M.; Henrion, Annabelle; Martinerie, E.; Molière, Fanny; Noisette, B.; Olié, E.; Tarquini, G.; Azorin, Jean‐Michel; Belzeaux, Raoul; Corréard, N.; Consoloni, Julia-Lou; Groppi, F.; Lescalier, Lauriane; Montant, J.; Rebattu, M.; Viglianese, N.; F. Cohen, Renaud; Kahn, Jean‐Pierre; Milazzo, Maria; Wajsbrot‐Elgrabli, O.; Bougerol, Thierry; Fredembach, B.; Denoual, Q.; Bertrand, Anne; Pouchon, Arnaud; Polosan, Mircea; Brehon, L.; Bony, G.; Durand, L; Feuga, V.; Kayser, N.; Passerieux, Christine; Roux, Paul; Aubin, V.; Cussac, I.; Dupont, Mickaël; Loftus, J.; Medecin, I.; Dubertret, Caroline; Mazer, Nicolas; Portalier, C.; Scognamiglio, C.; Bing, A.; Laurent, Paôline; Beal, Charlotte; Blanc, Olivier; Bonnet, Timothée; Lacelle, D.; Llorca, Pierre‐Michel; Mennetrier, M.; Samalin, Ludovic; Vayssié, M.; Bellivier, Frank; Étain, Bruno

doi:10.1038/s41398-024-02824-z

Public

Decreased telomere length in a subgroup of young individuals with bipolar disorders: replication in the FACE-BD cohort and association with the shelterin component POT1

Published in Translational Psychiatry • Mar 1, 2024

Authors:

Luana Spano

Cynthia Marie‐Claire

Ophélia Godin

Abstract

Bipolar disorder (BD) has been associated with premature cellular aging with shortened telomere length (TL) as compared to the general population. We recently identified a subgroup of young individuals with prematurely shortened TL. The aims of the present study were to replicate this observation in...

Subject

Shelterin

Telomere

Cohort

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