Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

Planas, Delphine; Staropoli, Isabelle; Michel, Vincent; Lemoine, Frédéric; Donati, Flora; Prot, Matthieu; Porrot, Françoise; Guivel‐Benhassine, Florence; Jeyarajah, Banujaa; Brisebarre, Angela; Dehan, Océane; Avon, Léa; Bolland, William; Hubert, Mathieu; Buchrieser, Julian; Vanhoucke, Thibault; Rosenbaum, Pierre; Veyer, David; Péré, Hélène; Lina, Bruno; Trouillet‐Assant, Sophie; Hocqueloux, Laurent; Prazuck, Thiérry; Simon‐Lorière, Etienne; Schwartz, Olivier

doi:10.1038/s41467-024-46490-7

Public

Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

Published in Nature Communications • Mar 13, 2024

Authors:

Delphine Planas

Isabelle Staropoli

Vincent Michel

Abstract

The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral sublineages. Here, we isolate and characterize XBB.1, XBB.1.5, XBB.1.9.1, XBB.1.16.1, EG.5.1.1, EG.5.1.3, XBF, BA.2.86.1 and JN.1 variants, representing >80% of circulating variants in January 2024. The XBB subv...

Subject

Antibody

Biology

Vero cell

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