Extended pleurectomy decortication and chemotherapy versus chemotherapy alone for pleural mesothelioma (MARS 2): a phase 3 randomised controlled trial

Lim, Eric; Waller, David; Lau, Kelvin; Steele, Jeremy; Pope, Anthony; Ali, Clinton; Bilancia, Rocco; Keni, Manjusha; Popat, Sanjay; O’Brien, Mary; Tokaca, Nadza; Maskell, Nick; Stadon, Louise; A. Fennell, Dean; Nelson, Louise; Edwards, John; Tenconi, Sara; Socci, Laura; C. Rintoul, Robert; Wood, Kelly; Stone, Amanda; Muthukumar, D.; Ingle, Charlotte; Taylor, Paul; Cove-Smith, Laura; Califano, Raffaele; Summers, Yvonne; Tasigiannopoulos, Z.; Billè, Andrea; Shah, Riyaz; Fuller, Elizabeth; MacNair, Andrew; Shamash, Jonathan; Mansy, T.; Milton, Richard; Koh, P.; Alina Ionescu, Andreea; Treece, Sarah; Roy, Amy; Middleton, Gary; Kirk, Alan; A Harris, Rosie; Ashton, Kate; Warnes, Barbara; Bridgeman, Emma; Joyce, Katherine; Mills, Nicola; Elliott, Daisy; Farrar, Nicola; A Stokes, Elizabeth; Hughes, Vikki; G. Nicholson, Andrew; Rogers, Chris

doi:10.1016/s2213-2600(24)00119-x

Public

Extended pleurectomy decortication and chemotherapy versus chemotherapy alone for pleural mesothelioma (MARS 2): a phase 3 randomised controlled trial

Published in The Lancet Respiratory Medicine • May 11, 2024

Authors:

Eric Lim

David Waller

Kelvin Lau

Abstract

BACKGROUND: Extended pleurectomy decortication for complete macroscopic resection for pleural mesothelioma has never been evaluated in a randomised trial. The aim of this study was to compare outcomes after extended pleurectomy decortication plus chemotherapy versus chemotherapy alone. METHODS: MARS...

Subject

Medicine

Pleurectomy

Decortication

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