Structure prediction analysis of human core <scp>TIM</scp> 23 complex reveals conservation of the protein translocation mechanism

K. Maruszczak, Klaudia; Drączkowski, Piotr; Wnorowski, Artur; Chacińska, Agnieszka

doi:10.1002/2211-5463.13840

Public

Structure prediction analysis of human core TIM 23 complex reveals conservation of the protein translocation mechanism

Published in FEBS Open Bio • Jun 4, 2024

Authors:

Klaudia K. Maruszczak

Piotr Drączkowski

Artur Wnorowski

Abstract

The majority of mitochondrial proteins are encoded in the nucleus, translated on cytosolic ribosomes, and subsequently targeted to the mitochondrial surface. Their further import into the organelle is facilitated by highly specialized protein translocases. Mitochondrial precursor proteins that are d...

Subject

Translocase

Translocase of the inner membrane

Mitochondrial carrier

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