Diagnostic performance of plasma pTau217, pTau181, Aβ1-42 and Aβ1-40 in the LUMIPULSE automated platform for the detection of Alzheimer disease

Arranz, Javier; Zhu, Nuole; Rubio‐Guerra, Sara; Rodríguez-Baz, Íñigo; Ferrer, Rosa; Carmona‐Iragui, María; Barroeta, Isabel; Illán-Gala, Ignacio; Santos‐Santos, Miguel; Fortea, Juan; Lleó, Alberto; Tondo, Mireia; Alcolea, Daniel

doi:10.1186/s13195-024-01513-9

Public

Diagnostic performance of plasma pTau217, pTau181, Aβ1-42 and Aβ1-40 in the LUMIPULSE automated platform for the detection of Alzheimer disease

Published in Alzheimer s Research & Therapy • Jun 26, 2024

Authors:

Javier Arranz

Nuole Zhu

Sara Rubio‐Guerra

Abstract

Abstract Background Recently developed blood markers for Alzheimer's disease (AD) detection have high accuracy but usually require ultra-sensitive analytic tools not commonly available in clinical laboratories, and their performance in clinical practice is unknown. Methods We analyzed plasma samples...

Subject

Concordance

Dementia

Medicine

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