An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

M. Marshall, Christopher; G. Federice, John; N. Bell, Chloe; B. Cox, Philip; T. Njardarson, Jón

doi:10.1021/acs.jmedchem.4c01122

Public

An Update on the Nitrogen Heterocycle Compositions and Properties of U.S. FDA-Approved Pharmaceuticals (2013–2023)

Published in Journal of Medicinal Chemistry • Jul 12, 2024

Authors:

Christopher M. Marshall

John G. Federice

Chloe N. Bell

Abstract

This Perspective is a continuation of our analysis of U.S. FDA-approved small-molecule drugs (1938–2012) containing nitrogen heterocycles. In this study we report drug structure and property analyses of 321 unique new small-molecule drugs approved from January 2013 to December 2023 as well as inform...

Subject

Chemistry

Combinatorial chemistry

Pharmacology

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