Development of a versatile [68Ga]Ga-FAPI-46 automated synthesis suitable to multi-elutions of germanium-68/gallium-68 generators

Paty, Louis-Paul; Degueldre, Simon; Provost, C.; Schmitt, Camille; Trump, Laura; Fouque, Julien; Vriamont, Charles; Valla, Frank; Gendron, Thibault; Madar, Olivier

doi:10.3389/fchem.2024.1411312

Public

Development of a versatile [68Ga]Ga-FAPI-46 automated synthesis suitable to multi-elutions of germanium-68/gallium-68 generators

Published in Frontiers in Chemistry • Jul 15, 2024

Authors:

Louis-Paul Paty

Simon Degueldre

C. Provost

Abstract

Gallium-68-labeled FAPI-46 has recently been proposed as a novel positron emission tomography imaging probe to diagnose and monitor a wide variety of cancers. Promising results from several ongoing clinical trials have led to a soaring demand for this radiotracer. Typical [ 68 Ga]Ga-FAPI-46 labeling...

Subject

Gallium

Germanium

Materials science

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