Role of inflammation and immune response in the pathogenesis of uterine fibroids: Including their negative impact on reproductive outcomes

Ishikawa, Hiroshi; Goto, Yuki; Hirooka, Chigusa; Katayama, Eri; Baba, Nao; Kaneko, Meika; Saito, Yoshiko; Kobayashi, Tatsuya; Koga, Kaori

doi:10.1016/j.jri.2024.104317

Public

Role of inflammation and immune response in the pathogenesis of uterine fibroids: Including their negative impact on reproductive outcomes

Published in Journal of Reproductive Immunology • Aug 15, 2024

Authors:

Hiroshi Ishikawa

Yuki Goto

Chigusa Hirooka

Abstract

Uterine fibroids (UFs), the most common tumors in women of reproductive age, are characterized by sex steroid-dependent growth and excessive deposition of extracellular matrix (ECM) surrounding UF smooth muscle cells. Women with symptomatic UFs experience heavy menstrual bleeding and consequent iron...

Subject

Inflammation

Pathogenesis

Uterine fibroids

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!