Release of mitochondrial dsRNA into the cytosol is a key driver of the inflammatory phenotype of senescent cells

The escape of mitochondrial double-stranded dsRNA (mt-dsRNA) into the cytosol has been recently linked to a number of inflammatory diseases. Here, we report that the release of mt-dsRNA into the cytosol is a general feature of senescent cells and a critical driver of their inflammatory secretome, kn... View More