How to build the virtual cell with artificial intelligence: Priorities and opportunities

Bunne, Charlotte; Roohani, Yusuf; Rosen, Yanay; Gupta, Ankit; Zhang, Xikun; Roed, Marcel; Alexandrov, Theodore; AlQuraishi, Mohammed; Flatley Brennan, Patrícia; B. Burkhardt, Daniel; Califano, Andrea; Cool, Jonah; F. Dernburg, Abby; Ewing, Kirsty; B. Fox, Emily; Haury, Matthias; E. Herr, Amy; Horvitz, Eric; D. Hsu, Patrick; Jain, Viren; R. Johnson, Gregory; Kalil, Thomas; R. Kelley, David; O. Kelley, Shana; Kreshuk, Anna; Mitchison, Tim; Otte, Stephani; Shendure, Jay; Sofroniew, Nicholas; J. Theis, Fabian; V. Theodoris, Christina; Upadhyayula, Srigokul; Valer, M.; Wang, Bo; P. Xing, Eric; Yeung-Levy, Serena; Žitnik, Marinka; Karaletsos, Theofanis; Regev, Aviv; Lundberg, Emma; Leskovec, Jure; R. Quake, Stephen

doi:10.1016/j.cell.2024.11.015

Public

How to build the virtual cell with artificial intelligence: Priorities and opportunities

Published in Cell • Dec 1, 2024

Authors:

Charlotte Bunne

Yusuf Roohani

Yanay Rosen

Abstract

Cells are essential to understanding health and disease, yet traditional models fall short of modeling and simulating their function and behavior. Advances in AI and omics offer groundbreaking opportunities to create an AI virtual cell (AIVC), a multi-scale, multi-modal large-neural-network-based mo...

Subject

Biology

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