Proximal Tubule-on-Chip for Predicting Cation Transport: Dynamic Insights into Drug Transporter Expression and Function

I, Petit; Q, Faucher; J, Bernard; P, Giunchi; A, Humeau; F, Sauvage; P, Marquet; N, Védrenne; FD, Meo

doi:10.1101/2024.10.12.617976

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Proximal Tubule-on-Chip for Predicting Cation Transport: Dynamic Insights into Drug Transporter Expression and Function

Shared by NobleBlocks on Oct 15, 2024 • 12:00 AM UTC

Authors:

Petit I

Faucher Q

Bernard J

Abstract

Deciphering the sources of variability in drug responses requires to understand the processes modulating drug pharmacokinetics. However, pharmacological research suffers from poor reproducibility across clinical, animal, and experimental models. Predictivity can be improved by using Organs-on-Chips,...

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