Safety, tolerability and pharmacokinetics of subcutaneous meropenem as an alternative to intravenous administration

Murray, Fionnuala; Yoo, Okhee; Brophy-Williams, Samuel; Rawlins, Matthew; C. Wallis, Steven; A. Roberts, Jason; Raby, Edward; Salman, Sam; Manning, Laurens

doi:10.1093/jac/dkae398

Public

Safety, tolerability and pharmacokinetics of subcutaneous meropenem as an alternative to intravenous administration

Published in Journal of Antimicrobial Chemotherapy • Nov 11, 2024

Authors:

Fionnuala Murray

Okhee Yoo

Samuel Brophy-Williams

Abstract

BACKGROUND: Subcutaneous delivery of antibiotics is a practical alternative to IV administration. Meropenem is commonly used to treat infections caused by resistant Gram-negative organisms. METHODS: This was a prospective, crossover self-controlled study in 11 stable inpatients established on merope...

Subject

Meropenem

Tolerability

Pharmacokinetics

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