Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children

Gupta, Sumit; E. Rau, Rachel; A. Kairalla, John; R. Rabin, Karen; Wang, Cindy; Angiolillo, Anne; Alexander, Sarah; J. Carroll, Andrew; J. Conway, Susan; Gore, Lia; Kirsch, Ilan; R. Kubaney, Holly; M. Li, Amanda; L. McNeer, Jennifer; Militano, Olga; P. Miller, Tamara; Moyer, Yvonne; M. O’Brien, Maureen; Okada, Maki; C. Reshmi, Shalini; Shago, Mary; M. Wagner, Elizabeth; Winick, Naomi; L. Wood, Brent; Haworth-Wright, Tara; Zaman, Faraz; Zugmaier, Gerhard; Zupanec, Sue; Devidas, Meenakshi; P. Hunger, Stephen; T. Teachey, David; A. Raetz, Elizabeth; L. Loh, Mignon

doi:10.1056/nejmoa2411680

Public

Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children

Published in New England Journal of Medicine • Dec 7, 2024

Authors:

Sumit Gupta

Rachel E. Rau

John A. Kairalla

Abstract

BACKGROUND: B-cell acute lymphoblastic leukemia (B-cell ALL) is the most common childhood cancer. Despite a high overall cure rate, relapsed B-cell ALL remains a leading cause of cancer-related death among children. The addition of the bispecific T-cell engager molecule blinatumomab (an anti-CD19 an...

Subject

Blinatumomab

Lymphoblastic Leukemia

Medicine

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