Pharmacokinetic Boosting of Calcineurin Inhibitors in Transplantation: Pros, Cons, and Perspectives.

S, Pattanaik; C, Monchaud

doi:10.1097/ftd.0000000000001288

Public

Pharmacokinetic Boosting of Calcineurin Inhibitors in Transplantation: Pros, Cons, and Perspectives.

Shared by NobleBlocks on Dec 24, 2024 • 12:00 AM UTC

Authors:

Pattanaik S

Monchaud C

Abstract

Abstract The concept of pharmacokinetic (PK) boosting of calcineurin inhibitors (CNI) emerged after the FDA approval of cyclosporine-A. Several studies followed, and the proof of concept was well established by the late 1990s. This also continued for the next blockbuster immunosuppressant, tacrolimu...

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