Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke

Huang, Jiacheng; Yang, Jie; Liu, Chang; Li, Linyu; Yang, Dahong; Guo, Changwei; Zeng, Guoyong; Song, Jiaxing; Ma, Jinfu; Xu, Xu; Shi, Xiaolei; Yang, Shihai; Sun, Wenzhe; Wang, Zhi‐Xi; Tang, Yufeng; Jiang, Maojun; Wang, Li; Cheng, Xiangping; Luo, Jun; Zhou, Peiyang; Fang, Xing; Cheng, Guangsen; Ruan, Zhongfan; Li, Jinglun; Liu, Jincheng; Lei, Bo; Tian, Yaoyu; Tan, Xiaolin; Yuan, Guangxiong; Wang, Jian; Huang, Xinyuan; Deng, Shengling; Jin, Zhenglong; Zou, Xin; Zhang, Jie; Cheng, Daoyou; Luo, Xiao‐Jun; Liao, Jiasheng; Miao, Jian; Li, Zhenqiang; Sun, Yaxuan; Jiang, Guohui; Kong, Deyan; Jiang, Shuyu; Wang, Zhiyuan; Wang, Duolao; Kaesmacher, Johannes; N. Nguyen, Thanh; G. Nogueira, Raul; L. Saver, Jeffrey; Chen, Yangmei; Zi, Wenjie; Investigators, POST-TNK; Li, Shuhui; Huang, Chuming; Ni, Yang; Duan, Zuowei; Guo, Junqing; Ni, Huafu; Zheng, Bo; Li, Fengli; Yu, Nizhen; Peng, Zhouzhou; Kong, Weilin; Liu, Xiang; Fan, Shitao; Yue, Chengsong; Song, Min; Chen, Gong; Huang, Liping

doi:10.1001/jama.2024.23466

Public

Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke

Published in JAMA • Jan 13, 2025

Authors:

Jiacheng Huang

Jie Yang

Chang Liu

Abstract

Importance: The impact of adjunctive intra-arterial tenecteplase administration following near-complete to complete reperfusion by endovascular thrombectomy (EVT) for acute ischemic stroke is unknown. Objective: To assess the efficacy and adverse events of adjunctive intra-arterial tenecteplase in p...

Subject

Medicine

Tenecteplase

Thrombolysis

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