Non-serous ovarian cancer in PTEN Hamartoma Tumor Syndrome: additional evidence for increased risk

J. Schei‐Andersen, Ane; M. Witjes, Vera; R. Vos, Janet; R. Mensenkamp, Arjen; M. van Altena, Anne; Schieving, Jolanda; Simons, Michiel; Schuurs-Hoeijmakers, Janneke; Study Group, PTEN; A. Adank, Muriel; P. van Hest, Liselotte; van Ierland, Yvette; de Jong, M.; C.J. Jongmans, Marjolijn; M. Leter, Edward; Nielsen, Maartje; Hoogerbrugge, Nicoline

doi:10.1007/s10689-025-00453-z

Public

Non-serous ovarian cancer in PTEN Hamartoma Tumor Syndrome: additional evidence for increased risk

Published in Familial Cancer • Mar 18, 2025

Authors:

Ane J. Schei‐Andersen

Vera M. Witjes

Janet R. Vos

Abstract

Increased hereditary cancer risk is one of the hallmarks of PTEN Hamartoma Tumor Syndrome (PHTS) which is caused by a pathogenic germline variant in PTEN. Case reports and some cohort studies have described ovarian cancer (OC) in PHTS patients. Previously, we observed an enrichment of non-serous OC ...

Subject

PTEN

Cowden syndrome

Serous fluid

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!