Safety, Functional Disability, Healthcare Utilization, and Quality-of-Life Outcomes in Elderly Receiving Alteplase and Tenecteplase: A Secondary Analysis From the AcT Trial

Singh, Nishita; Bala, Fouzi; Ademola, Ayoola; Almekhlafi, Mohammed; B. Coutts, Shelagh; Deschaintre, Yan; Khosravani, Houman; Buck, Brian; Appireddy, Ramana; Moreau, F.; Gubitz, Gord; Tkach, Aleksander; Catanese, Luciana; Dowlatshahi, Dar; Medvedev, George; Mandzia, Jennifer; Pikula, Aleksandra; Shankar, Jai; Y. Poppe, Alexandre; Williams, Heather; S. Field, Thalia; Alejandro Manosalva Alzate, Herbert; Siddiqui, Muzaffar; Zafar, Atif; Imoukhoude, Oje; Hunter, Gary; Shamy, Michel; M. Demchuk, Andrew; H. Swartz, Richard; D. Hill, Michael; T. Sajobi, Tolulope; K. Menon, Bijoy; Ganesh, Aravind

doi:10.1161/strokeaha.124.049512

Public

Safety, Functional Disability, Healthcare Utilization, and Quality-of-Life Outcomes in Elderly Receiving Alteplase and Tenecteplase: A Secondary Analysis From the AcT Trial

Published in Stroke • Mar 24, 2025

Authors:

Nishita Singh

Fouzi Bala

Ayoola Ademola

Abstract

BACKGROUND: Older age has been associated with overall poorer outcomes in acute ischemic stroke. We compared (1) outcomes in various health-related domains among patients <80 years and ≥80 years presenting with acute ischemic stroke and (2) whether outcomes differ between intravenous TNK (tenectepla...

Subject

Medicine

Tenecteplase

Modified Rankin Scale

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