Outcomes of Patients With Extramedullary Disease in Triple-Class Exposed Relapsed/Refractory Multiple Myeloma From the Pooled LocoMMotion and MoMMent Studies

Moreau, Philippe; Mateos, María-Victoria; Goldschmidt, Hartmut; Esther González García, María; Besemer, Britta; Sonia González, Marta; Mohty, Mohamad; Lindsey-Hill, Joanne; Kirkpatrick, Suriya; Delforge, Michel; Angelucci, Emanuele; Di Raimondo, Francesco; Vij, Ravi; Doyle, Margaret; Gray, Kathleen; Albrecht, Claire; Strulev, Vadim; Haddad, Imène; Koskinen, Silva; Acciarri, Lorenzo; Buyze, Jozefien; Weisel, Katja

doi:10.1016/j.clml.2025.03.014

Public

Outcomes of Patients With Extramedullary Disease in Triple-Class Exposed Relapsed/Refractory Multiple Myeloma From the Pooled LocoMMotion and MoMMent Studies

Published in Clinical Lymphoma Myeloma & Leukemia • Mar 30, 2025

Authors:

Philippe Moreau

María-Victoria Mateos

Hartmut Goldschmidt

Abstract

BACKGROUND: Patients with relapsed/refractory multiple myeloma (RRMM) who develop extramedullary disease (EMD) generally have a poor prognosis, highlighting the urgent need for new therapies. We report effectiveness outcomes and safety in patients with and without EMD from the pooled analysis of Loc...

Subject

Medicine

Multiple myeloma

Refractory (planetary science)

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