Marine Guanidine Alkaloids Inhibit Malaria Parasites Development in In Vitro, In Vivo and Ex Vivo Assays

Rossi Mendes, Giovana; L. Noronha, Anderson; M. R. Moura, Igor; M. Moreira, Natália; Bonatto, Vinícius; de Souza Barbosa, Camila; El Chamy Maluf, Sarah; de Souza, Guilherme; R. de Amorim, Marcelo; Caroline Campos Aguiar, Anna; C. Cruz, Fábio; dos Santos Ferreira, Amália; Bioni Garcia Teles, Carolina; B. Pereira, Dhélio; Hajdu, Eduardo; G. Ferreira, Antônio; G. S. Berlinck, Roberto; V. C. Guido, Rafael

doi:10.1021/acsinfecdis.4c00714

Public

Marine Guanidine Alkaloids Inhibit Malaria Parasites Development in In Vitro, In Vivo and Ex Vivo Assays

Published in ACS Infectious Diseases • Apr 15, 2025

Authors:

Giovana Rossi Mendes

Anderson L. Noronha

Igor M. R. Moura

Abstract

High Resolution Image Download MS PowerPoint Slide Malaria is a disease caused by pathogenic protozoa Plasmodium spp., with a significant global impact on human health. Increasing resistance of P. falciparum strains to drugs treating malaria highlights the urgent need for the discovery of new antima...

Subject

Plasmodium falciparum

Malaria

In vivo

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