Abstract 6608: Integrating HCMI models and tumors with CCLE and TCGA: Advancing cancer modeling and precision oncology

ElHarouni, Dina; Al‐Jazrawe, Mushriq; Choi, Seongmin; Dede, Merve; Hinoue, Toshinori; A. Misek, Sean; Noh, Heeju; Zanella, Luca; Tseng, Moony; E. Francies, Hayley; Sridevi, Priya; Agarwal, Rachana; W. Kyi, Cindy; Pérez‐Mayoral, Julyann; J. Stine, Megan; Tonsing-Carter, Eva; M. Clinton, James; HCMI Network, The; W. Laird, Peter; J. Kuo, Calvin; Elemento, Olivier; L. Spector, David; D. Cherniack, Andrew; Ellrott, Kyle; L. Ferguson, Martin; Beroukhim, Rameen; A. Hoadley, Katherine; Robine, Nicolas; McPherson, Andrew; J. Garnett, Mathew; A. Tuveson, David; Califano, Andrea; T. Spellman, Paul; L. Ligon, Keith; S. Gerhard, Daniela; M. Staudt, Louis; S. Boehm, Jesse

doi:10.1158/1538-7445.am2025-6608

Public

Abstract 6608: Integrating HCMI models and tumors with CCLE and TCGA: Advancing cancer modeling and precision oncology

Published in Cancer Research • Apr 21, 2025

Authors:

Dina ElHarouni

Mushriq Al‐Jazrawe

Seongmin Choi

Abstract

Abstract The Human Cancer Models Initiative (HCMI) has developed 665 novel cancer models, including organoids and matched parental tumors, providing a significant addition to existing cancer model resources. To evaluate the transcriptional relatedness of HCMI models and tumors to the Cancer Cell Lin...

Subject

Medicine

Precision oncology

Internal medicine

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