Dissecting immune-mediated pathways in rheumatoid arthritis: A multivariate mediation analysis of antibodies and circulating proteins.

J, Niu; P, Zhang; W, Liu; S, Sun; Y, Zhang; J, Sang; J, Yang; Q, Zhang; L, Chai

doi:10.1038/s41598-025-01216-7

Public

Dissecting immune-mediated pathways in rheumatoid arthritis: A multivariate mediation analysis of antibodies and circulating proteins.

Shared by NobleBlocks on May 14, 2025 • 12:00 AM UTC

Authors:

Niu J

Zhang P

Liu W

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disorder with complex etiologies involving immune responses and circulating proteins. This study investigates the causal relationships between antibody immune responses, plasma circulating proteins, and the development of RA using Mendelian Randomi...

Subject

Rheumatoid arthritis

Epstein-Barr virus

Mendelian Randomization

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