Deciphering human endogenous retrovirus expression in colorectal cancers: exploratory analysis regarding prognostic value in liver metastases

Viot, Julien; Loyon, Romain; Adib, Nawfel; Laurent‐Puig, Pierre; de Reyniès, Aurélien; André, Fabrice; Monnien, Franck; André, Thierry; Svrcek, Magali; Turpin, Anthony; Selmani, Zohair; Arnould, Laurent; Guyard, Laura; Gilbert, Nicolas; Boureux, Anthony; Adotévi, Olivier; Vienot, Angélique; Abdeljaoued, Syrine; Vernerey, Déwi; Borg, Christophe; Gautheret, Daniel

doi:10.1016/j.ebiom.2025.105727

Public

Deciphering human endogenous retrovirus expression in colorectal cancers: exploratory analysis regarding prognostic value in liver metastases

Published in EBioMedicine • May 16, 2025

Authors:

Julien Viot

Romain Loyon

Nawfel Adib

Abstract

BACKGROUND: Human Endogenous RetroVirus (HERV) expression in tumours reflects epigenetic dysregulation of cancer and an oncogenic factor through promoter/enhancer action on genes. While more than 50% of colorectal cancers develop liver metastases, HERV has not been studied in this context. METHODS: ...

Subject

Colorectal cancer

Endogenous retrovirus

Value (mathematics)

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