Precision nanomedicine: navigating the tumor microenvironment for enhanced cancer immunotherapy and targeted drug delivery

Sabit, Hussein; M. Pawlik, Timothy; F.Y. Radwan, Faisal; Abdel-Hakeem, Mohamed; Abdel-Ghany, Shaimaa; Soliman Wadan, Al-Hassan; El-Zawahri, Mokhtar; El-Hashash, Ahmed; Arneth, Borros

doi:10.1186/s12943-025-02357-z

Public

Precision nanomedicine: navigating the tumor microenvironment for enhanced cancer immunotherapy and targeted drug delivery

Published in Molecular Cancer • Jun 3, 2025

Authors:

Hussein Sabit

Timothy M. Pawlik

Faisal F.Y. Radwan

Abstract

Cancer treatment has been revolutionized by immunotherapy and nanomedicine, offering innovative strategies to overcome the tumor microenvironment (TME) complexities. However, challenges such as therapeutic resistance, off-target effects, and immune suppression necessitate advanced delivery systems a...

Subject

Nanomedicine

Tumor microenvironment

Immunotherapy

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