Postoperative 20% Albumin Infusion and Acute Kidney Injury in High-Risk Cardiac Surgery Patients

Shehabi, Yahya; Balachandran, Mayurathan; Al‐Bassam, Wisam; Bailey, Michael; Bellomo, Rinaldo; Bihari, Shailesh; Brown, Alana; Brown, Alastair; W. Collins, David; R. Darlison, Phoebe; Li, Mozhu; Mandarano, Raffaele; Sarode, Vineet; Pakavakis, Adrian; AKI Study Investigators, ALBICS; J. Glassford, Neil; Grant, Peter; Harington, Claire; Raymond, Lewis; Dougherty, Lisa; Maeda, Akinori; Chaba, Anis; Phongphithakchai, Atthaphong; M. Eastwood, Glenn; Spano, Sofia; Young, Helen; Peck, Leah; Bleetman, David; Holmes, Jennifer; King, Melissa; Ordering, Adelle; H. Y. Luk, V.; McIntyre, Joanne; Bottari, Vanessa; Olivo, Giuseppe; Galeotti, Ilaria; Albano, Francesco; Paul, Eldo

doi:10.1001/jamasurg.2025.1683

Public

Postoperative 20% Albumin Infusion and Acute Kidney Injury in High-Risk Cardiac Surgery Patients

Published in JAMA Surgery • Jun 11, 2025

Authors:

Yahya Shehabi

Mayurathan Balachandran

Wisam Al‐Bassam

Abstract

Importance: Acute kidney injury (AKI) after cardiac surgery is a common and serious complication. Protein loading appears nephroprotective; thus, continuous hyperoncotic albumin infusion may impact AKI following high-risk cardiac surgery. Objective: To evaluate the effect of postoperative 20% albumi...

Subject

Medicine

Acute kidney injury

Albumin

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